SCHEMBL2585364

SCHEMBL2585364

CO[Si]1(OC)CCCOCC(CN2CCCCCC2)O1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
ADRA2C P18825 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
SCN1A P35498 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN3A Q9NY46 1/20 0.33
CHRM5 P08912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2575144 1.00 GAA (0.35) GAAADRA2CADRA2AADRA2BADRA1D
SCHEMBL2577690 0.93 GAA (0.40) GAA
SCHEMBL301451 0.90 HRH3 (0.34) GAA
SCHEMBL2577710 0.89 ACHE (0.36) GAA
SCHEMBL2581021 0.87 GAA (0.33) GAAADRA2CADRA2AADRA2BADRA1D
SCHEMBL2577639 0.87 GAA (0.33) GAAADRA2CADRA2AADRA2BADRA1D
SCHEMBL2582384 0.84 GAA (0.35) GAAADRA2CADRA2AADRA2BADRA1D
SCHEMBL2575355 0.79 GAA (0.39) GAA
SCHEMBL2525121 0.78
SCHEMBL2581450 0.78 GAA (0.33) GAAADRA2CADRA2AADRA2BADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8049027-B2 Organosilicon compound having amino group and its production method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-11-01 US disclosed
EP-2180001-A1 Organosilicon compound having amino group and its production method Shin-Etsu Chemical Co., Ltd. (JP) 2010-04-28 EP disclosed
US-20100099866-A1 ORGANOSILICON COMPOUND HAVING AMINO GROUP AND ITS PRODUCTION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099866-A1 ORGANOSILICON COMPOUND HAVING AMINO GROUP AND ITS PRODUCTION METHOD HRH3, H1-0, H1-2 GAA 4182/4885ADRA2C 2525/4885ADRA2A 2334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.