Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14737217 | 0.90 | PDE4D (0.43) | PDE4DTP53MAOB | |
| SCHEMBL14738673 | 0.88 | PDE4D (0.43) | PDE4DTP53MAOB | |
| SCHEMBL2591715 | 0.87 | PDE4D (0.44) | PDE4DTP53MAOB | |
| SCHEMBL2589772 | 0.87 | PDE4D (0.43) | PDE4DTP53MAOB | |
| SCHEMBL2589438 | 0.87 | PDE4D (0.44) | PDE4DTP53MAOB | |
| SCHEMBL2594344 | 0.86 | PDE4D (0.38) | PDE4DMEN1KMT2AMAOB | |
| SCHEMBL2592376 | 0.85 | PDE4D (0.43) | PDE4DTP53MAOB | |
| SCHEMBL14737568 | 0.85 | PDE4D (0.43) | PDE4DTP53MAOB | |
| SCHEMBL2584140 | 0.85 | PDE4D (0.43) | PDE4DTP53MAOB | |
| SCHEMBL14737147 | 0.84 | PDE4D (0.44) | PDE4DMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563770-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134468-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-11-03 | — | — | WO | disclosed |