SCHEMBL25854605

SCHEMBL25854605

C=C1COc2ccccc2C1[C@H](C)C(=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
MGAM O43451 1/20 0.39
AMY1A P0DUB6 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
POLB P06746 2/20 0.38
ALDH1A1 P00352 6/20 0.36
KDM4E B2RXH2 5/20 0.36
MAPT P10636 3/20 0.36
APEX1 P27695 1/20 0.36
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
RECQL P46063 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25854609 0.86 GAA (0.41) GAAMGAMAMY1ASIMGAM2
SCHEMBL25854537 0.81 HTR2A (0.42) TSHRL3MBTL1MEN1KMT2APIN1
SCHEMBL25854656 0.81 ALDH1A1 (0.32) ALDH1A1ATMMEN1KMT2ATP53
SCHEMBL25854610 0.78 POLB (0.36) GAAMGAMAMY1ASIMGAM2
SCHEMBL22877253 0.78 CYP3A4 (0.37) GAAALDH1A1KDM4ETSHRHPGD
SCHEMBL26704971 0.75 ALDH1A1 (0.40) GAAALDH1A1KDM4ETSHRHPGD
SCHEMBL26429694 0.75 BCHE (0.39) GAAMGAMAMY1ASIMGAM2
SCHEMBL25859235 0.72 POLB (0.38) GAAMGAMAMY1ASIMGAM2
SCHEMBL29617345 0.72 CYP1A2 (0.45) POLBALDH1A1KDM4EMAPTTSHR
SCHEMBL28926885 0.72 CYP1A2 (0.45) POLBALDH1A1KDM4EMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227437-A1 IMMUNOMODULATOR IL17A, IL2, IL2RA GAA 2382/4885MGAM 2305/4885AMY1A 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.