Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475420 | 0.88 | GAA (0.58) | GAAALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL30475423 | 0.88 | GAA (0.58) | GAAALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL10090771 | 0.83 | HTT (0.62) | GAAALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL11137615 | 0.78 | HTT (0.67) | ALDH1A1KMT2AHTTSMN1; SMN2NPC1 | |
| SCHEMBL682171 | 0.77 | GAA (0.57) | GAAALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31531040 | 0.75 | MEN1 (0.62) | GAAKMT2AHTTSMN1; SMN2ATM | |
| SCHEMBL10308040 | 0.75 | MEN1 (0.62) | GAAKMT2AHTTSMN1; SMN2ATM | |
| SCHEMBL11086324 | 0.75 | KMT2A (0.76) | ALDH1A1KMT2AHTTSMN1; SMN2NPC1 | |
| SCHEMBL17372922 | 0.75 | HTT (0.56) | GAAALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4385506 | 0.74 | ALPL (0.58) | GAAALDH1A1KMT2AHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131677-A1 | COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-07-13 | — | — | WO | disclosed |