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SCHEMBL25854663

SCHEMBL25854663

C=CC(=O)OCCCc1ccc(-c2ccc3c(sc4cc(OC(=O)C=C)ccc43)c2C(F)(F)F)cc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 3/20 0.38
▸ ESR1 P03372 2/20 0.31
▸ ESR2 Q92731 1/20 0.31
▸ FFAR1 O14842 2/20 0.30
▸ PPARD Q03181 1/20 0.30
▸ FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25854441 0.89 THRB (0.40) THRBESR1ESR2FFAR1FFAR4
SCHEMBL25854669 0.89 THRB (0.37) THRBESR1ESR2FFAR1FFAR4
SCHEMBL25854576 0.87 ESR1 (0.33) THRBESR1
SCHEMBL25854566 0.86 THRB (0.42) THRBESR1ESR2FFAR1FFAR4
SCHEMBL25856102 0.86 THRB (0.35) THRB
SCHEMBL25854571 0.86 THRB (0.41) THRBESR1ESR2
SCHEMBL25853302 0.85 THRB (0.34) THRB
SCHEMBL25855863 0.85 THRB (0.34) THRB
SCHEMBL25854665 0.84 POLB (0.33) ESR1ESR2
SCHEMBL25854943 0.84 THRB (0.33) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 — — WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 — — WO disclosed