Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25854704 | 0.81 | EPHX2 (0.41) | KMT2ASMN1; SMN2 | |
| SCHEMBL27021613 | 0.81 | MAOB (0.33) | MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL13593980 | 0.81 | MAOB (0.33) | MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL31637667 | 0.76 | EPHX1 (0.31) | — | |
| SCHEMBL12920576 | 0.75 | MAPT (0.33) | MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL23841989 | 0.75 | KMT2A (0.35) | MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL21023565 | 0.73 | IRAK4 (0.31) | KMT2ASMN1; SMN2 | |
| SCHEMBL15113275 | 0.71 | — | — | |
| SCHEMBL31424982 | 0.71 | — | — | |
| SCHEMBL25854709 | 0.70 | KMT2A (0.53) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708348-B2 | Protease inhibitors for treatment of coronavirus infections | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708348-B2 | Protease inhibitors for treatment of coronavirus infections | ACE, ACE2, TMPRSS2 | MAOB 326/4885KMT2A 2364/4885SMN1; SMN2 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.