Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25854691 | 0.81 | MAOB (0.34) | KMT2ASMN1; SMN2 | |
| SCHEMBL24568981 | 0.79 | EPHX2 (0.37) | EPHX2IDO1 | |
| SCHEMBL25543880 | 0.77 | KMT2A (0.31) | KMT2ASMN1; SMN2 | |
| SCHEMBL25545350 | 0.77 | GRM1 (0.36) | KMT2ASMN1; SMN2 | |
| SCHEMBL25857001 | 0.75 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL22758640 | 0.74 | IDO1 (0.40) | IDO1 | |
| SCHEMBL17582410 | 0.72 | EPHX2 (0.39) | EPHX2 | |
| SCHEMBL29791363 | 0.71 | EPHX2 (0.39) | EPHX2IDO1SMN1; SMN2 | |
| SCHEMBL25854709 | 0.71 | KMT2A (0.53) | EPHX2KMT2ASMN1; SMN2 | |
| SCHEMBL21023565 | 0.71 | IRAK4 (0.31) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708348-B2 | Protease inhibitors for treatment of coronavirus infections | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708348-B2 | Protease inhibitors for treatment of coronavirus infections | ACE, ACE2, TMPRSS2 | EPHX2 2636/4885IDO1 1238/4885KMT2A 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.