SCHEMBL25855172

SCHEMBL25855172

CC(C)N1CC(N2CCC3(CC2)CN(C)C3)C1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 8/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29316986 0.90 HRH3 (0.46) HRH3
SCHEMBL29316995 0.83 HRH3 (0.37) HRH3
SCHEMBL22565052 0.83 HRH3 (0.34) HRH3
SCHEMBL24827895 0.81 HRH3 (0.43) HRH3
SCHEMBL22565976 0.80 HRH3 (0.40) HRH3
SCHEMBL26743370 0.79 HRH3 (0.33) HRH3
SCHEMBL25855894 0.79 HRH3 (0.40) HRH3
SCHEMBL26427872 0.79 HRH3 (0.45) HRH3
SCHEMBL10128466 0.78 CYP2D6 (0.39) HRH3
SCHEMBL22565155 0.77 HRH3 (0.43) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131167-A1 COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF 海思科医药集团股份有限公司 2023-07-13 WO disclosed