SCHEMBL25855894

SCHEMBL25855894

CC(C)N1CC(N2CC3(CCC(N4CCN(C)CC4)CC3)C2)C1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 11/20 0.40
L3MBTL3 Q96JM7 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29316986 0.83 HRH3 (0.46) HRH3
SCHEMBL29316995 0.83 HRH3 (0.37) HRH3
SCHEMBL12030772 0.82 MC4R (0.31) HRH3L3MBTL3L3MBTL1
SCHEMBL25855172 0.79 HRH3 (0.45) HRH3
SCHEMBL24828011 0.78 HRH3 (0.35) HRH3
SCHEMBL25574868 0.78 HRH3 (0.44) HRH3L3MBTL3L3MBTL1
SCHEMBL19116639 0.76 HRH3 (0.36) HRH3
SCHEMBL8255509 0.74 MEN1 (0.35) HRH3L3MBTL3L3MBTL1
SCHEMBL24996654 0.74 HRH3 (0.40) HRH3
SCHEMBL21077359 0.73 HRH3 (0.34) HRH3L3MBTL3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131167-A1 COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF 海思科医药集团股份有限公司 2023-07-13 WO disclosed