Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 15/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30068760 | 0.90 | MAP3K12 (0.39) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL25303031 | 0.90 | MAP3K12 (0.39) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL30491391 | 0.90 | MAP3K12 (0.38) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL25306277 | 0.90 | MAP3K12 (0.38) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL30068603 | 0.90 | MAP3K12 (0.38) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL25302977 | 0.90 | MAP3K12 (0.38) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL25299934 | 0.90 | MAP3K12 (0.38) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL30068812 | 0.90 | MAP3K12 (0.38) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL25844391 | 0.89 | MAP3K12 (0.39) | MAP3K12METPIK3CGABL1 | |
| SCHEMBL30491538 | 0.85 | MET (0.41) | MAP3K12METPIK3CGABL1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |