Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 2/20 | 0.30 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.30 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108885 | 0.90 | NLRP3 (0.64) | NLRP3KCNH2TNFIL1B | |
| SCHEMBL25855087 | 0.83 | NLRP3 (0.49) | NLRP3KCNH2TNFIL1BLATS1 | |
| SCHEMBL27224408 | 0.81 | NLRP3 (0.74) | NLRP3KCNH2TNFIL1B | |
| SCHEMBL30157063 | 0.81 | NLRP3 (0.74) | NLRP3KCNH2TNFIL1B | |
| Hydrochloric Acid SCHEMBL27224466 | 0.80 | NLRP3 (0.73) | NLRP3KCNH2TNFIL1B | |
| SCHEMBL30932864 | 0.80 | NLRP3 (0.73) | NLRP3KCNH2TNFIL1B | |
| Hydrochloric Acid SCHEMBL30157098 | 0.80 | NLRP3 (0.73) | NLRP3KCNH2TNFIL1B | |
| SCHEMBL25302297 | 0.80 | NLRP3 (0.57) | NLRP3IL1B | |
| SCHEMBL25303433 | 0.80 | NLRP3 (0.57) | NLRP3IL1B | |
| SCHEMBL25854954 | 0.80 | NLRP3 (0.57) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |