SCHEMBL25855661 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NLRP3	Q96P20	6/20	0.55

▸	IL1B	P01584	9/20	0.43

▸	TNF	P01375	2/20	0.43

▸	KDM4E	B2RXH2	2/20	0.35

▸	GAA	P10253	2/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	LMNA	P02545	1/20	0.35

▸	HTT	P42858	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

▸	HSD17B10	Q99714	1/20	0.34

▸	MAPT	P10636	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25855664	0.92	NLRP3 (0.55)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL30517797	0.92	NLRP3 (0.55)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL25257459	0.92	NLRP3 (0.55)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL25855653	0.91	NLRP3 (0.56)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL25304800	0.91	NLRP3 (0.56)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL25855659	0.90	NLRP3 (0.53)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL25855665	0.90	NLRP3 (0.55)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL25855662	0.90	NLRP3 (0.55)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL25864311	0.89	NLRP3 (0.44)	NLRP3IL1BTNFKDM4EGAA
SCHEMBL25855656	0.89	NLRP3 (0.52)	NLRP3IL1BTNFKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023131277-A1	NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF	药捷安康(南京)科技股份有限公司	2023-07-13	—	—	WO	disclosed