Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21436976 | 0.90 | STING1 (0.67) | STING1 | |
| SCHEMBL25855979 | 0.86 | STING1 (0.48) | STING1 | |
| SCHEMBL21406404 | 0.83 | STING1 (0.72) | STING1 | |
| SCHEMBL21454650 | 0.83 | STING1 (0.65) | STING1ACHE | |
| SCHEMBL25855952 | 0.81 | STING1 (0.70) | STING1 | |
| SCHEMBL25855950 | 0.81 | STING1 (0.70) | STING1 | |
| SCHEMBL21405741 | 0.81 | STING1 (0.67) | STING1 | |
| SCHEMBL30416880 | 0.81 | STING1 (0.67) | STING1 | |
| SCHEMBL25855963 | 0.81 | STING1 (0.83) | STING1 | |
| SCHEMBL25855969 | 0.81 | STING1 (0.83) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702430-B2 | Aza-benzothiophene compounds as STING agonists | MERCK SHARP & DOHME LLC (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702430-B2 | Aza-benzothiophene compounds as STING agonists | STING1, IRF3, CGAS | STING1 1/4885ACHE 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.