Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.67 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21405741 | 1.00 | STING1 (0.67) | STING1TBXAS1ALOX15ATMBCL2L1 | |
| SCHEMBL21406404 | 0.85 | STING1 (0.72) | STING1 | |
| SCHEMBL21436976 | 0.84 | STING1 (0.67) | STING1 | |
| SCHEMBL21405952 | 0.84 | STING1 (0.49) | STING1BCL2L1GPR35 | |
| SCHEMBL30416399 | 0.83 | STING1 (0.58) | STING1PIK3CG | |
| SCHEMBL21406360 | 0.83 | STING1 (0.58) | STING1PIK3CG | |
| SCHEMBL21454650 | 0.82 | STING1 (0.65) | STING1 | |
| SCHEMBL22887142 | 0.82 | STING1 (0.65) | STING1 | |
| SCHEMBL25855947 | 0.81 | STING1 (0.64) | STING1 | |
| SCHEMBL21454707 | 0.81 | STING1 (1.00) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |