Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.67 |
| ▸ | IL1B | P01584 | 9/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25854843 | 0.91 | NLRP3 (0.68) | NLRP3IL1BTNF | |
| SCHEMBL25854841 | 0.90 | NLRP3 (0.67) | NLRP3IL1BTNFKCNH2 | |
| SCHEMBL25864425 | 0.90 | NLRP3 (0.54) | NLRP3IL1BTNFKCNH2 | |
| SCHEMBL25854844 | 0.90 | NLRP3 (0.64) | NLRP3IL1BTNFKCNH2 | |
| SCHEMBL25855967 | 0.89 | NLRP3 (0.65) | NLRP3IL1BTNFKCNH2 | |
| SCHEMBL25854738 | 0.88 | NLRP3 (0.69) | NLRP3IL1BTNFKCNH2 | |
| SCHEMBL25854849 | 0.87 | NLRP3 (0.68) | NLRP3IL1BTNFKCNH2 | |
| SCHEMBL25854625 | 0.86 | NLRP3 (0.66) | NLRP3IL1BTNFKCNH2 | |
| SCHEMBL25855827 | 0.83 | NLRP3 (0.48) | NLRP3IL1BTNFKCNH2 | |
| SCHEMBL25855970 | 0.83 | NLRP3 (0.68) | NLRP3IL1BTNFKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |