Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474066 | 0.83 | IDO1 (0.58) | IDO1CA1CA2GPR84SLC6A4 | |
| SCHEMBL2991124 | 0.80 | IDO1 (0.55) | IDO1CA1CA2GPR84HTT | |
| SCHEMBL2996997 | 0.79 | IDO1 (0.54) | IDO1CA1CA2GPR84HTT | |
| SCHEMBL10445642 | 0.79 | IDO1 (0.54) | IDO1CA1CA2GPR84SLC6A4 | |
| SCHEMBL29617530 | 0.77 | IDO1 (0.50) | IDO1CA1CA2PTPN7HTR6 | |
| SCHEMBL1878272 | 0.77 | IDO1 (0.50) | IDO1CA1CA2PTPN7HTR6 | |
| SCHEMBL2992195 | 0.77 | IDO1 (0.51) | IDO1GPR84HTTALDH1A1FFAR1 | |
| SCHEMBL20874509 | 0.77 | HTR6 (0.48) | CA1CA2HTR6 | |
| SCHEMBL1520601 | 0.76 | IDO1 (1.00) | IDO1GPR84SLC6A4 | |
| SCHEMBL15330041 | 0.76 | IDO1 (0.72) | IDO1GPR84SLC6A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123135-A1 | Methods To Identify Modulators of TAS2R48 Receptors | GIVAUDAN SA (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130115624-A1 | Methods To Identify Modulators | GIVAUDAN S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
| EP-2567231-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138456-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |