Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.53 |
| ▸ | IL1B | P01584 | 9/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25864643 | 0.90 | NLRP3 (0.42) | NLRP3IL1BTNF | |
| SCHEMBL25854620 | 0.87 | NLRP3 (0.56) | NLRP3IL1BTNF | |
| SCHEMBL25862667 | 0.87 | NLRP3 (0.56) | NLRP3IL1BTNF | |
| SCHEMBL25856154 | 0.85 | NLRP3 (0.54) | NLRP3IL1BTNF | |
| SCHEMBL25856155 | 0.85 | NLRP3 (0.54) | NLRP3IL1BTNF | |
| SCHEMBL25300762 | 0.80 | NLRP3 (0.56) | NLRP3IL1BTNF | |
| SCHEMBL30488479 | 0.80 | NLRP3 (0.56) | NLRP3IL1BTNF | |
| SCHEMBL29030532 | 0.79 | NLRP3 (0.81) | NLRP3IL1BTNF | |
| SCHEMBL29030520 | 0.79 | NLRP3 (0.78) | NLRP3IL1BTNF | |
| SCHEMBL30488489 | 0.79 | NLRP3 (0.81) | NLRP3IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |