SCHEMBL25856164

SCHEMBL25856164

C=C(C)C(=O)OCCCc1ccc(-c2ccc3c(c2)sc2c(OC(F)(F)F)c(OC(=O)C(=C)C)ccc23)cc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.31
SLC13A5 Q86YT5 1/20 0.31
PIK3CA P42336 2/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25854084 0.93 POLB (0.32) POLBAPEX1HTTTDP1
SCHEMBL25855453 0.89 PDE4A (0.34) MCL1PIK3CAPOLBAPEX1HTT
SCHEMBL25855864 0.89 NR1H2 (0.33) MCL1PIK3CAPOLBAPEX1HTT
SCHEMBL25856377 0.88 FFAR4 (0.31) POLBAPEX1HTTTDP1
SCHEMBL25860724 0.87 MCL1 (0.33) MCL1PIK3CAPOLBAPEX1HTT
SCHEMBL25855042 0.86 MCL1 (0.35) MCL1PIK3CAPOLBAPEX1HTT
SCHEMBL25856224 0.86 MPL (0.31) POLBAPEX1HTTTDP1
SCHEMBL25854670 0.85 POLB (0.32) POLBAPEX1HTTTDP1
SCHEMBL25856320 0.85 FFAR4 (0.33)
SCHEMBL25856162 0.85 KMT2A (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed