SCHEMBL25855453

SCHEMBL25855453

C=C(C)C(=O)OCCCc1ccc(-c2ccc3c(c2)sc2c(OC)c(OC(=O)C(=C)C)ccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 5/20 0.34
PDE4B Q07343 5/20 0.34
PDE4C Q08493 5/20 0.34
PDE4D Q08499 5/20 0.34
MCL1 Q07820 1/20 0.33
ESR1 P03372 2/20 0.32
ESR2 Q92731 1/20 0.32
MET P08581 3/20 0.32
AKR1B10 O60218 1/20 0.32
AKR1B1 P15121 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PIK3CA P42336 2/20 0.32
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25853771 0.92 TNKS2 (0.34) METAKR1B10AKR1B1TNKS2POLB
SCHEMBL25855042 0.90 MCL1 (0.35) PDE4APDE4BPDE4CPDE4DMCL1
SCHEMBL25856164 0.89 MCL1 (0.31) MCL1POLBAPEX1HTTTDP1
SCHEMBL25860724 0.89 MCL1 (0.33) PDE4APDE4BPDE4CPDE4DMCL1
SCHEMBL25855748 0.87 TNKS2 (0.33) METAKR1B10AKR1B1TNKS2POLB
SCHEMBL25855864 0.86 NR1H2 (0.33) MCL1POLBAPEX1HTTTDP1
SCHEMBL25854572 0.84 ESR1 (0.36) ESR1ESR2TNKS2POLBAPEX1
SCHEMBL25855451 0.84 MET (0.37) PDE4APDE4BPDE4CPDE4DMCL1
SCHEMBL25855449 0.84 TUBB4A (0.39) ESR1HTTTUBB4ATUBBTUBA3C
SCHEMBL25869086 0.83 POLB (0.39) MCL1ESR1ESR2POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed