Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22570086 | 0.86 | CHRM5 (0.53) | CHRM5ADRA2CACHESMN1; SMN2KDM4E | |
| SCHEMBL4132048 | 0.85 | CHRM5 (0.67) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| SCHEMBL16271017 | 0.85 | CHRM5 (0.67) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| SCHEMBL4132043 | 0.85 | CHRM5 (0.67) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| SCHEMBL1204165 | 0.84 | CHRM5 (0.42) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| SCHEMBL24474498 | 0.84 | CHRM5 (0.50) | CHRM5ADRA2CACHESMN1; SMN2KDM4E | |
| SCHEMBL30697248 | 0.84 | CHRM5 (0.50) | CHRM5ADRA2CACHESMN1; SMN2KDM4E | |
| SCHEMBL842660 | 0.83 | CHRM5 (0.39) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| SCHEMBL372637 | 0.83 | CHRM5 (0.39) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| SCHEMBL372638 | 0.83 | CHRM5 (0.39) | CHRM5ADRA2CACHEKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |