Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24474498 | 1.00 | CHRM5 (0.50) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| SCHEMBL22570086 | 0.98 | CHRM5 (0.53) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| SCHEMBL842660 | 0.92 | CHRM5 (0.39) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| SCHEMBL372638 | 0.92 | CHRM5 (0.39) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| SCHEMBL372637 | 0.92 | CHRM5 (0.39) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL19002912 | 0.91 | CHRM5 (0.38) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL19002911 | 0.91 | CHRM5 (0.38) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL3487702 | 0.91 | CHRM5 (0.38) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL3487703 | 0.91 | CHRM5 (0.38) | CHRM5ADRA2CACHEKDM4ETDP1 | |
| SCHEMBL1204165 | 0.89 | CHRM5 (0.42) | CHRM5ADRA2CACHEKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416271-A1 | HETEROARYLQUINAZOLINE COMPOUNDS AS PROTEIN KINASE INHIBITORS | Chengdu Cynogen Bio-Pharmaceutical Technology Co., Ltd. (CN) | 2023-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416271-A1 | HETEROARYLQUINAZOLINE COMPOUNDS AS PROTEIN KINASE INHIBITORS | CDK9, CDK2, CDK6 | CHRM5 4880/4885ADRA2C 4361/4885ACHE 4567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.