Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633019 | 0.86 | GRM4 (0.37) | GRM4ERBB2NAMPT | |
| Hydrochloric Acid SCHEMBL30464353 | 0.85 | GRM4 (0.37) | GRM4ERBB2NAMPT | |
| Hydrochloric Acid SCHEMBL19614868 | 0.80 | ERBB2 (0.38) | GRM4ERBB2 | |
| Hydrochloric Acid SCHEMBL30464368 | 0.80 | ERBB2 (0.38) | GRM4ERBB2 | |
| Trifluoroacetic Acid SCHEMBL30944465 | 0.80 | BACE1 (0.35) | BACE1 | |
| Trifluoroacetic Acid SCHEMBL30944518 | 0.77 | BACE1 (0.33) | BACE1 | |
| SCHEMBL19633219 | 0.76 | AGPAT2 (0.40) | GRM4NAMPT | |
| SCHEMBL19614843 | 0.73 | GRM4 (0.36) | GRM4ERBB2NAMPT | |
| SCHEMBL19633039 | 0.73 | ERBB2 (0.40) | GRM4ERBB2NAMPT | |
| SCHEMBL19636843 | 0.73 | GRM4 (0.35) | GRM4BACE1ERBB2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458069-B1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | MERSANA THERAPEUTICS INC (US) | 2023-07-05 | — | — | EP | disclosed |