Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15425110 | 0.82 | MKNK1 (0.64) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25305249 | 0.81 | MAPT (0.65) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL27460988 | 0.76 | RAB9A (0.57) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL12491621 | 0.75 | RAB9A (0.64) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10890200 | 0.73 | MAPT (0.54) | MAPTTP53MEN1KMT2APOLB | |
| SCHEMBL10889952 | 0.73 | MAPT (0.48) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL16682342 | 0.71 | GAA (0.59) | MAPTCA12CA1CA2CA4 | |
| SCHEMBL25308935 | 0.71 | MAPT (0.67) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL25263437 | 0.71 | MAPT (0.52) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL3842147 | 0.69 | RAB9A (0.79) | MAPTTP53NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130540-A1 | PYRAZOL BENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州大学 | 2023-07-13 | — | — | WO | disclosed |