Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | KLK7 | P49862 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PPIB | P23284 | 1/20 | 0.31 |
| ▸ | STK10 | O94804 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856728 | 0.82 | KDM4E (0.39) | CNR1CNR2L3MBTL1KDM4EHPGD | |
| SCHEMBL25856719 | 0.81 | ATM (0.39) | CNR1CNR2L3MBTL1KDM4EHPGD | |
| SCHEMBL25856903 | 0.80 | PGR (0.38) | CNR1CNR2KDM4EHPGDHSD17B10 | |
| SCHEMBL23523917 | 0.79 | SMN1; SMN2 (0.55) | L3MBTL1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL30355447 | 0.79 | SMN1; SMN2 (0.55) | L3MBTL1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL30355716 | 0.78 | NPC1 (0.47) | CNR1CNR2KDM4EHPGDHSD17B10 | |
| SCHEMBL23524423 | 0.78 | CNR1 (0.40) | CNR1CNR2PTPRCPTPN1L3MBTL1 | |
| SCHEMBL30355702 | 0.78 | CNR1 (0.40) | CNR1CNR2PTPRCPTPN1L3MBTL1 | |
| SCHEMBL23524076 | 0.78 | NPC1 (0.47) | CNR1CNR2KDM4EHPGDHSD17B10 | |
| SCHEMBL25856218 | 0.78 | CNR1 (0.34) | CNR1CNR2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | CNR1 20/4885CNR2 38/4885PTPRC 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.