Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.50 |
| ▸ | HTR7 | P34969 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507804 | 0.82 | HRH3 (0.56) | TAAR1HRH3HTR7MEN1ALDH1A1 | |
| SCHEMBL25430010 | 0.79 | TAAR1 (0.55) | TAAR1HRH3HTR7MEN1ALDH1A1 | |
| SCHEMBL20918900 | 0.78 | SKP2 (0.46) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9378588 | 0.77 | HPGD (0.40) | HRH3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27798768 | 0.77 | SKP2 (0.59) | TAAR1HRH3HTR7MEN1ALDH1A1 | |
| SCHEMBL6915886 | 0.76 | TAAR1 (0.50) | TAAR1HTR7ALDH1A1TP53CYP1A2 | |
| SCHEMBL1099654 | 0.76 | ALDH1A1 (0.47) | MEN1ALDH1A1CYP1A2MAPTCYP2C19 | |
| SCHEMBL17704659 | 0.74 | ESR1 (0.48) | MEN1ALDH1A1MAPTCYP2C19KMT2A | |
| SCHEMBL3931779 | 0.74 | SKP2 (0.61) | MEN1ALDH1A1TP53CYP1A2MAPT | |
| SCHEMBL18762839 | 0.73 | HRH3 (0.84) | TAAR1HRH3MEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |