Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258498 | 0.95 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL258612 | 0.94 | TSHR (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13109395 | 0.94 | TSHR (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL19291628 | 0.84 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL258535 | 0.84 | THRB (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL720774 | 0.82 | TSHR (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16744077 | 0.82 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL124287 | 0.82 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13109375 | 0.81 | TSHR (0.45) | TSHR | |
| SCHEMBL23064056 | 0.81 | TSHR (0.56) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |