⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24770547 | 0.91 | CACNA1H (0.31) | — | |
| SCHEMBL25744947 | 0.84 | — | — | |
| SCHEMBL24769110 | 0.82 | MAP3K12 (0.32) | — | |
| SCHEMBL24770545 | 0.81 | MAPT (0.35) | — | |
| SCHEMBL25857831 | 0.80 | — | — | |
| SCHEMBL24768318 | 0.78 | — | — | |
| SCHEMBL25744946 | 0.77 | — | — | |
| SCHEMBL24768317 | 0.77 | — | — | |
| SCHEMBL24770343 | 0.75 | CACNA1G (0.30) | — | |
| SCHEMBL25857838 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357254-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-09 | — | — | US | disclosed |
| US-11702422-B2 | Imidazopyridazines as modulators of IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-07-18 | — | — | US | disclosed |