⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857231 | 0.82 | — | — | |
| SCHEMBL26575937 | 0.76 | DYRK1A (0.36) | — | |
| SCHEMBL25744929 | 0.76 | — | — | |
| SCHEMBL25857803 | 0.72 | IRAK4 (0.31) | — | |
| SCHEMBL7650649 | 0.71 | IDO1 (0.37) | — | |
| SCHEMBL23957806 | 0.70 | EGLN2 (0.33) | — | |
| SCHEMBL13031208 | 0.70 | MEN1 (0.31) | — | |
| SCHEMBL20121775 | 0.70 | HRH4 (0.31) | — | |
| SCHEMBL12364368 | 0.70 | NTRK1 (0.32) | — | |
| SCHEMBL7602678 | 0.70 | ACHE (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357254-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-09 | — | — | US | disclosed |
| US-11702422-B2 | Imidazopyridazines as modulators of IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-07-18 | — | — | US | disclosed |