SCHEMBL25857887

SCHEMBL25857887

c1ccc(C2(c3ccccc3-c3cccc4c3C(c3ccccc3)(c3ccccc3)c3ccccc3O4)c3ccccc3-c3cc4ccccc4cc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
OPRK1 P41145 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPK1 P28482 2/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857891 0.97 KDM4E (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25848419 0.92 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25866770 0.90 KDM4E (0.39) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25857279 0.89 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25848523 0.89 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25848168 0.89 PDK2 (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25848077 0.89 KDM4E (0.37) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25857706 0.89 KDM4E (0.34) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25867010 0.88 PDK2 (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25865774 0.86 KDM4E (0.41) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed