SCHEMBL25866770

SCHEMBL25866770

c1ccc(C2(c3ccc(-c4cccc5c4C(c4ccccc4)(c4ccccc4)c4ccccc4O5)cc3)c3ccccc3-c3cc4ccccc4cc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
OPRK1 P41145 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857037 0.98 KDM4E (0.39) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25867010 0.93 PDK2 (0.33) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25857279 0.92 KDM4E (0.35) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25848168 0.92 PDK2 (0.33) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25848523 0.92 KDM4E (0.33) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25857887 0.90 KDM4E (0.36) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25866769 0.90 MEN1 (0.44) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25856908 0.90 KDM4E (0.37) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25857286 0.89 KDM4E (0.35) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL25856915 0.88 MEN1 (0.39) KDM4EMEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed