SCHEMBL25857934

SCHEMBL25857934

C#Cc1ccc(-c2nnc(NC)nc2C2CC2)c(O)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 6/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31496020 0.84 NLRP3 (0.31) NLRP3
SCHEMBL31314328 0.82 EGLN1 (0.31)
SCHEMBL25861616 0.81 NLRP3 (0.39) NLRP3
SCHEMBL25858061 0.80 AXL (0.31)
SCHEMBL31548627 0.80 NLRP3 (0.52) NLRP3
SCHEMBL30488485 0.80 NLRP3 (0.52) NLRP3
SCHEMBL25856238 0.80 NLRP3 (0.52) NLRP3
SCHEMBL29030494 0.80 NLRP3 (0.52) NLRP3
SCHEMBL25860146 0.78 NLRP3 (0.31) NLRP3
SCHEMBL25860307 0.78 EGFR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131277-A1 NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF 药捷安康(南京)科技股份有限公司 2023-07-13 WO disclosed