SCHEMBL25857976

SCHEMBL25857976

COc1c(C)ccc2c1sc1c(OC(F)(F)F)c(C)ccc12

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 1/20 0.30
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25858055 0.93 SCN8A (0.33) SCN8A
SCHEMBL25857971 0.87 SCN8A (0.30) SCN8A
SCHEMBL25858046 0.86 KDM4E (0.37) MEN1USP2MAPTALOX15KMT2A
SCHEMBL25858054 0.85 HDAC3 (0.31)
SCHEMBL25858049 0.84
SCHEMBL25857975 0.82
SCHEMBL25857974 0.79 HDAC3 (0.33) MEN1USP2MAPTALOX15KMT2A
SCHEMBL25857970 0.79 KDM4E (0.34) MEN1USP2MAPTALOX15KMT2A
SCHEMBL25858051 0.78 GPR3 (0.33)
SCHEMBL12433435 0.73 SCN8A (0.36) SCN8AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed