Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 19/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25853128 | 0.91 | MAPK1 (0.55) | MAPK1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25852058 | 0.90 | MAPK1 (0.53) | MAPK1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25852947 | 0.90 | MAPK1 (0.54) | MAPK1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25857373 | 0.89 | MAPK1 (0.53) | MAPK1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25970915 | 0.84 | MAPK1 (0.54) | MAPK1 | |
| SCHEMBL18891669 | 0.83 | MAPK1 (0.78) | MAPK1 | |
| SCHEMBL25852706 | 0.83 | MAPK1 (0.51) | MAPK1 | |
| SCHEMBL25852109 | 0.82 | MAPK1 (0.47) | MAPK1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21558013 | 0.82 | MAPK1 (0.54) | MAPK1 | |
| SCHEMBL21541562 | 0.82 | MAPK1 (0.54) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |