Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776493 | 0.88 | GPR119 (0.45) | USP30GPR119KDM4E | |
| SCHEMBL25426082 | 0.84 | GPR119 (0.49) | USP30GPR119 | |
| SCHEMBL30381457 | 0.84 | GPR119 (0.49) | USP30GPR119 | |
| SCHEMBL16040735 | 0.81 | GPR119 (0.40) | GPR119KDM4EMAPTTHRBHSD17B10 | |
| SCHEMBL29774310 | 0.81 | GPR119 (0.44) | GPR119BACE1KDM4EMAPTTHRB | |
| SCHEMBL20839829 | 0.81 | GPR119 (0.44) | GPR119BACE1KDM4EMAPTTHRB | |
| SCHEMBL25339058 | 0.80 | USP30 (0.42) | USP30GPR119FPR2KDM4EALDH2 | |
| SCHEMBL22776965 | 0.80 | STS (0.45) | GPR119MAPT | |
| SCHEMBL29978778 | 0.80 | STS (0.45) | GPR119MAPT | |
| SCHEMBL25303941 | 0.78 | FLT3 (0.37) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |