Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21949466 | 0.89 | LPL (0.44) | LPLLIPGHIF1ACA12CA1 | |
| SCHEMBL23520385 | 0.84 | LPL (0.39) | LPLLIPGHIF1ACA12CA1 | |
| SCHEMBL25858474 | 0.81 | LPL (0.36) | LPLLIPGHIF1ACA12CA1 | |
| SCHEMBL2429070 | 0.80 | LPL (0.49) | LPLLIPGHIF1ACA12CA1 | |
| SCHEMBL2428529 | 0.78 | LPL (0.47) | LPLLIPGHIF1ACA12CA1 | |
| SCHEMBL2424883 | 0.77 | LPL (0.49) | LPLLIPGHIF1ACA12CA1 | |
| SCHEMBL19966320 | 0.76 | HIF1A (0.33) | LPLLIPGHIF1AESR2 | |
| SCHEMBL18332596 | 0.76 | LPL (0.42) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL19204154 | 0.75 | LPL (0.39) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL2427419 | 0.75 | LPL (0.47) | LPLLIPGHIF1ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |