Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25261543 | 0.91 | BRD4 (0.47) | BRD4ADORA2AADORA1OPRM1OPRD1 | |
| SCHEMBL25857417 | 0.83 | BRD4 (0.46) | BRD4ADORA2AADORA1OPRM1OPRD1 | |
| SCHEMBL25307292 | 0.82 | ADORA2A (0.52) | BRD4ADORA2AADORA1OPRM1OPRD1 | |
| SCHEMBL29435907 | 0.82 | BRD4 (0.46) | BRD4ADORA2AADORA1OPRM1OPRD1 | |
| SCHEMBL25308682 | 0.82 | BRD4 (0.46) | BRD4ADORA2AADORA1OPRM1OPRD1 | |
| SCHEMBL29435895 | 0.82 | ADORA2A (0.52) | BRD4ADORA2AADORA1OPRM1OPRD1 | |
| SCHEMBL25388991 | 0.79 | ADORA2A (0.65) | ADORA2AADORA1 | |
| SCHEMBL29435912 | 0.79 | ADORA2A (0.65) | ADORA2AADORA1 | |
| SCHEMBL30473266 | 0.78 | BRD4 (0.48) | BRD4OPRM1OPRD1OGFRL1MEN1 | |
| SCHEMBL8861190 | 0.70 | OPRM1 (0.58) | BRD4ADORA1OPRM1OPRD1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130701-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | 中山大学 | 2023-07-13 | — | — | WO | disclosed |