Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 7/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | KISS1R | Q969F8 | 5/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857993 | 0.87 | CYP3A4 (0.42) | CYP3A4FOLH1FAPTTR | |
| SCHEMBL22198583 | 0.83 | CYP3A4 (0.52) | CYP3A4FOLH1KISS1RSSTR2FAP | |
| SCHEMBL25859965 | 0.83 | CYP3A4 (0.52) | CYP3A4FOLH1KISS1RSSTR2FAP | |
| SCHEMBL25854069 | 0.83 | CYP3A4 (0.57) | CYP3A4FOLH1KISS1RSSTR2FAP | |
| SCHEMBL20382894 | 0.83 | CYP3A4 (0.57) | CYP3A4FOLH1KISS1RSSTR2FAP | |
| SCHEMBL26223056 | 0.81 | CYP3A4 (0.38) | CYP3A4FOLH1FAPCTSBCTSK | |
| SCHEMBL25859949 | 0.81 | CYP3A4 (0.55) | CYP3A4FOLH1KISS1RSSTR2FAP | |
| SCHEMBL19869062 | 0.80 | FOLH1 (0.40) | CYP3A4FOLH1KISS1RFAPTTR | |
| SCHEMBL20095233 | 0.80 | FOLH1 (0.40) | CYP3A4FOLH1KISS1RFAPTTR | |
| SCHEMBL25833839 | 0.79 | CYP3A4 (0.41) | CYP3A4FOLH1KISS1RFAPTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | BICYCLETX LIMITED (GB) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | EPHA2, EPHB2, ERBB2 | CYP3A4 4184/4885NPBWR1 503/4885FOLH1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.