Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | FURIN | P09958 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP4 | P49662 | 1/20 | 0.32 |
| ▸ | CASP5 | P51878 | 1/20 | 0.32 |
| ▸ | CASP9 | P55211 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.32 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095233 | 0.94 | FOLH1 (0.40) | CYP3A4FOLH1FAPTTRFURIN | |
| SCHEMBL19869062 | 0.94 | FOLH1 (0.40) | CYP3A4FOLH1FAPTTRFURIN | |
| SCHEMBL25829056 | 0.93 | CYP3A4 (0.40) | CYP3A4FOLH1FAPTTRFURIN | |
| SCHEMBL22241542 | 0.91 | CYP3A4 (0.37) | CYP3A4FOLH1FAPTTRL3MBTL1 | |
| SCHEMBL20095333 | 0.91 | CYP3A4 (0.37) | CYP3A4FOLH1FAPTTRL3MBTL1 | |
| SCHEMBL21444704 | 0.90 | FOLH1 (0.38) | CYP3A4FOLH1FAPTTRFURIN | |
| SCHEMBL27352417 | 0.89 | FOLH1 (0.40) | CYP3A4FOLH1FAPTTRFURIN | |
| SCHEMBL27349556 | 0.89 | FOLH1 (0.40) | CYP3A4FOLH1FAPTTRFURIN | |
| SCHEMBL25857993 | 0.88 | CYP3A4 (0.42) | CYP3A4FOLH1FAPTTRL3MBTL1 | |
| SCHEMBL20385923 | 0.88 | CYP3A4 (0.46) | CYP3A4FOLH1FAPTTRFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-11701427-B2 | Diels-alder conjugation methods | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | GLUL, TGM2, GLS | CYP3A4 1943/4885FOLH1 14/4885FAP 577/4885 |
| US-11701427-B2 | Diels-alder conjugation methods | GLUL, TGM2, GLS | CYP3A4 1943/4885FOLH1 14/4885FAP 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.