Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26745375 | 0.88 | CRBN (0.44) | CRBNDDB1BRD4 | |
| SCHEMBL20805224 | 0.80 | DDB1 (0.58) | CRBNDDB1 | |
| SCHEMBL30273914 | 0.80 | DDB1 (0.58) | CRBNDDB1 | |
| SCHEMBL25567327 | 0.76 | DDB1 (0.55) | CRBNDDB1 | |
| SCHEMBL25862450 | 0.75 | DDB1 (0.50) | CRBNDDB1 | |
| SCHEMBL25857318 | 0.75 | DDB1 (0.48) | CRBNDDB1 | |
| SCHEMBL25566700 | 0.75 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL31101167 | 0.75 | CRBN (0.62) | CRBNDDB1 | |
| SCHEMBL21733021 | 0.74 | PDK2 (0.47) | — | |
| SCHEMBL19585876 | 0.73 | DDB1 (1.00) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |