SCHEMBL25859479

SCHEMBL25859479

C=C1COc2cc(F)c(F)cc2C1CC(=O)OCC

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
USP2 O75604 1/20 0.34
HTT P42858 1/20 0.34
CYP11B1 P15538 3/20 0.34
CYP11B2 P19099 3/20 0.34
CYP1A2 P05177 1/20 0.33
DPP4 P27487 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
GLA P06280 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992536 0.69 CYP1A2 (0.36) MIFL3MBTL1CYP11B1CYP11B2CYP1A2
SCHEMBL22992364 0.68 CYP1A2 (0.48) CYP1A2
SCHEMBL14402121 0.67 PPARD (0.44)
SCHEMBL11836856 0.66 CYP1A2 (0.46) L3MBTL1CYP1A2MEN1KMT2AALDH1A1
SCHEMBL31674096 0.65 L3MBTL1 (0.48) L3MBTL1
SCHEMBL11622190 0.63 CYP1A2 (0.38) MIFUSP2HTTCYP1A2KMT2A
SCHEMBL24776233 0.63 L3MBTL1 (0.41) MIFL3MBTL1CYP1A2MEN1KMT2A
SCHEMBL22992504 0.62 POLB (0.52) L3MBTL1USP2CYP1A2MEN1KMT2A
SCHEMBL22992502 0.62 POLB (0.52) L3MBTL1USP2CYP1A2MEN1KMT2A
SCHEMBL9979486 0.61 FFAR1 (0.47) MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227437-A1 IMMUNOMODULATOR IL17A, IL2, IL2RA MIF 18/4885L3MBTL1 4577/4885USP2 3602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.