Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | PRCP | P42785 | 8/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19548054 | 0.94 | KCNH2 (0.66) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL2962436 | 0.94 | KCNH2 (0.66) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL14675018 | 0.90 | KCNH2 (0.73) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL692686 | 0.88 | KCNH2 (0.74) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL3241410 | 0.87 | KCNH2 (0.62) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL19548079 | 0.87 | KCNH2 (0.71) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL690397 | 0.87 | KCNH2 (0.71) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL692685 | 0.86 | KCNH2 (0.70) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL2586065 | 0.86 | KCNH2 (0.65) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 | |
| SCHEMBL2586059 | 0.86 | KCNH2 (0.65) | KCNH2OPRM1OPRD1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110268697-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110268697-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | KCNH2 4523/4885OPRM1 2169/4885OPRD1 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.