Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16730520 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1EPHX2PAOX | |
| SCHEMBL20283628 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1EPHX2PAOX | |
| SCHEMBL8214934 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1EPHX2PAOX | |
| Hydrochloric Acid SCHEMBL2579652 | 0.98 | TSHR (0.61) | TSHRLMNAALDH1A1EPHX2PAOX | |
| Hydrochloric Acid SCHEMBL2583424 | 0.98 | TSHR (0.61) | TSHRLMNAALDH1A1EPHX2PAOX | |
| SCHEMBL23132220 | 0.92 | TSHR (0.54) | TSHRLMNAALDH1A1EPHX2PAOX | |
| SCHEMBL132401 | 0.92 | TSHR (0.54) | TSHRLMNAALDH1A1EPHX2PAOX | |
| SCHEMBL13903720 | 0.92 | CA12 (0.59) | TSHRLMNAALDH1A1EPHX2CA12 | |
| SCHEMBL13903715 | 0.92 | CA12 (0.59) | TSHRLMNAALDH1A1EPHX2CA12 | |
| SCHEMBL18641686 | 0.92 | TSHR (0.54) | TSHRLMNAALDH1A1EPHX2PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269943-A1 | RADIOLABELED ANNEXINS | UNIVERSITY OF WASHINGTON (US) | 2011-11-03 | — | — | US | disclosed |
| EP-1426062-A2 | Radiolabeled annexins | NEORX CORPORATION (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-0918547-B1 | RADIOLABELED ANNEXINS | NEORX CORP (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20020137672-A1 | Radiolabeled annexins | KASINA SUDHAKAR (US) | 2002-09-26 | — | — | US | disclosed |
| US-5968477-A | IMAGING AGENTS WITH SULFHYDRYL GROUPS AND HEXOSE GROUPS | NEORX CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0918547-A2 | RADIOLABELED ANNEXINS | NEORX CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997046098-A9 | CLUSTER CLEARING AGENTS | — | 1998-08-06 | — | — | WO | disclosed |
| WO-1998004294-A2 | RADIOLABELED ANNEXINS | NEORX CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269943-A1 | RADIOLABELED ANNEXINS | ANXA11, ANXA1, ANXA3 | TSHR 679/4885LMNA 3549/4885ALDH1A1 4269/4885 |
| US-20020137672-A1 | Radiolabeled annexins | ANXA11, ANXA1, ANXA3 | TSHR 679/4885LMNA 3549/4885ALDH1A1 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.