Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.30 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258609 | 0.92 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL258615 | 0.88 | THRB (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL258495 | 0.83 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3681594 | 0.82 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13109396 | 0.81 | THRB (0.36) | TSHRTHRB | |
| SCHEMBL2173357 | 0.79 | CYP3A4 (0.45) | TSHRTDP1ALDH1A1 | |
| SCHEMBL13109376 | 0.78 | TSHR (0.41) | TSHRTHRBALDH1A1P2RY10GPR34 | |
| SCHEMBL8975865 | 0.77 | THRB (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL720282 | 0.77 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13109390 | 0.76 | THRB (0.31) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |