Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393481 | 0.88 | HPGD (0.46) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL1830482 | 0.85 | HPGD (0.48) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL7065136 | 0.85 | GPR119 (0.48) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL15110051 | 0.83 | GPR119 (0.45) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL16854650 | 0.83 | GPR119 (0.43) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL28891296 | 0.82 | GPR119 (0.46) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL14450372 | 0.82 | HPGD (0.46) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL13811514 | 0.81 | GPR119 (0.52) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL24680917 | 0.80 | USP30 (0.48) | GPR119HPGDRECQLEPHX1JAK2 | |
| SCHEMBL31208730 | 0.80 | USP30 (0.48) | GPR119HPGDRECQLEPHX1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |