SCHEMBL25864797

SCHEMBL25864797

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc(-c4cccc(-c5nc6ccccc6o5)c4)cc3)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 5/20 0.51
NPC1 O15118 7/20 0.50
RAB9A P51151 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ATM Q13315 1/20 0.50
PTGS2 P35354 2/20 0.47
ALDH1A1 P00352 6/20 0.47
KDM4E B2RXH2 6/20 0.47
HPGD P15428 5/20 0.47
SMN1; SMN2 Q16637 5/20 0.47
HSD17B10 Q99714 3/20 0.47
VSIR Q9H7M9 1/20 0.46
PKM P14618 1/20 0.45
HPSE Q9Y251 2/20 0.45
NFKB1 P19838 2/20 0.44
STAT1 P42224 2/20 0.44
NFKB2 Q00653 2/20 0.44
RELA Q04206 2/20 0.44
HCRTR1 O43613 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27049325 0.97 NPC1 (0.54) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL25864804 0.94 NPC1 (0.52) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL24184418 0.92 NPC1 (0.58) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL27293333 0.91 TP53 (0.50) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL27049323 0.91 NPC1 (0.56) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL27049318 0.91 NPC1 (0.56) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL20404975 0.91 NPC1 (0.60) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL27293899 0.90 TP53 (0.47) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL27049315 0.89 NPC1 (0.58) TP53NPC1RAB9AMEN1KMT2A
SCHEMBL23099323 0.89 NPC1 (0.52) TP53NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136586-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-20 WO disclosed