SCHEMBL25864804

SCHEMBL25864804

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccccc3-c3cccc(-c4ccc(-c5nc6ccccc6o5)cc4)c3)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.52
RAB9A P51151 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
ATM Q13315 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.49
HPGD P15428 4/20 0.49
HSD17B10 Q99714 4/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
TP53 P04637 2/20 0.49
PTGS2 P35354 3/20 0.48
MAPT P10636 2/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP13 P45452 1/20 0.44
CASP3 P42574 2/20 0.44
SENP7 Q9BQF6 2/20 0.44
SENP6 Q9GZR1 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27049325 0.96 NPC1 (0.54) NPC1RAB9AMEN1KMT2AATM
SCHEMBL25864797 0.94 TP53 (0.51) NPC1RAB9AMEN1KMT2AATM
SCHEMBL27293899 0.92 TP53 (0.47) NPC1RAB9AMEN1KMT2AATM
SCHEMBL23099323 0.90 NPC1 (0.52) NPC1RAB9AMEN1KMT2AATM
SCHEMBL27293333 0.90 TP53 (0.50) NPC1RAB9AMEN1KMT2AATM
SCHEMBL27049317 0.90 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL27049313 0.90 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL27049316 0.90 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL27049321 0.90 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL20404975 0.90 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136586-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-20 WO disclosed