Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenylpropanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylpropanol SCHEMBL16685501 | 1.00 | LMNA (0.91) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL539164 | 0.95 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL27878996 | 0.95 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL698860 | 0.95 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL56673 | 0.95 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL27691663 | 0.95 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL3489153 | 0.93 | LMNA (0.86) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL19667852 | 0.93 | LMNA (0.95) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL9994261 | 0.93 | LMNA (0.95) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL11694956 | 0.93 | LMNA (0.95) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109791377-A | Detergent composition is used in the removing of resin exposure mask | 花王株式会社 | 2019-05-21 | — | — | CN | disclosed |
| US-20110274994-A1 | Catalyst and Liquid Combination for a Thermally Regenerative Fuel Cell | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-11-10 | — | — | US | disclosed |