Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18925570 | 1.00 | MAPK8 (0.32) | MAPK8 | |
| Hydrochloric Acid SCHEMBL17311101 | 0.98 | MAPK8 (0.31) | MAPK8 | |
| SCHEMBL21144175 | 0.86 | — | — | |
| SCHEMBL29253020 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL22691254 | 0.84 | IDH1 (0.33) | — | |
| SCHEMBL104840 | 0.80 | MAPK8 (0.31) | MAPK8 | |
| SCHEMBL22430868 | 0.79 | — | — | |
| SCHEMBL18927996 | 0.77 | KCNH2 (0.35) | MAPK8 | |
| SCHEMBL21166035 | 0.77 | IDH1 (0.31) | MAPK8 | |
| SCHEMBL23097042 | 0.76 | EPHX2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837454-A | Synthesis method of 3,3-difluorocyclohexyl methylamine | 河南师范大学 | 2016-08-10 | — | — | CN | claimed |
| CN-104387279-B | A kind of method of easy synthesis 3,3-difiuorocyclohexyl methylamine | HENAN NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | claimed |
| CN-104387279-A | Method for simply synthesizing 3, 3-difluorocyclohexylmethylamine | UNIV HENAN NORMAL | 2015-03-04 | — | — | CN | claimed |
| WO-2023134608-A1 | FUSED RING COMPOUNDS SERVING AS HPK1 INHIBITORS | 微境生物医药科技(上海)有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-107207476-B | Indole and azaindole derivatives and their use in neurodegenerative diseases | 默克专利有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-105837454-B | A kind of synthetic method of 3,3- difiuorocyclohexyls methylamine | 河南师范大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-105837454-A | Synthesis method of 3,3-difluorocyclohexyl methylamine | 河南师范大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-105837454-A | Synthesis method of 3,3-difluorocyclohexyl methylamine | 河南师范大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-105837454-A | Synthesis method of 3,3-difluorocyclohexyl methylamine | 河南师范大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-104387279-B | A kind of method of easy synthesis 3,3-difiuorocyclohexyl methylamine | HENAN NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104387279-B | A kind of method of easy synthesis 3,3-difiuorocyclohexyl methylamine | HENAN NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104387279-A | Method for simply synthesizing 3, 3-difluorocyclohexylmethylamine | UNIV HENAN NORMAL | 2015-03-04 | — | — | CN | disclosed |