SCHEMBL23097042

SCHEMBL23097042

CNC1CCCCC(F)(F)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.35
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178464 0.89 EPHX2 (0.40) EPHX2KDM1A
Hydrochloric Acid SCHEMBL17818720 0.86 EPHX2 (0.39) EPHX2KDM1A
SCHEMBL25865746 0.76 MAPK8 (0.32)
SCHEMBL18925570 0.76 MAPK8 (0.32)
SCHEMBL168531 0.75
SCHEMBL999708 0.75 ALDH1A1 (0.60) EPHX2
SCHEMBL29253020 0.75
SCHEMBL26257045 0.75 ALDH1A1 (0.60) EPHX2
SCHEMBL21144175 0.75
Hydrochloric Acid SCHEMBL17311101 0.74 MAPK8 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3371174-B1 INDOLIN-2-ONE DERIVATIVES HOFFMANN LA ROCHE (CH) 2021-03-17 EP disclosed