SCHEMBL25865862

SCHEMBL25865862

CC(C)(C)[Si](C)(C)OC(CN)CN1CCOCC1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.38
ALDH1A1 P00352 3/20 0.35
ANPEP P15144 1/20 0.35
KEAP1 Q14145 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.32
MCHR1 Q99705 1/20 0.32
CYP2D6 P10635 1/20 0.31
ALOX15 P16050 1/20 0.31
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25866860 0.87 MEN1 (0.31) MEN1KMT2A
SCHEMBL25865575 0.86 MEN1 (0.33) ANPEPMEN1KMT2A
SCHEMBL7220461 0.84 KDM4E (0.32) KDM4E
SCHEMBL29235837 0.82 USP2 (0.40) USP2ALDH1A1ANPEPSMN1; SMN2MEN1
SCHEMBL25866774 0.81 USP2 (0.39) USP2ALDH1A1ANPEPSMN1; SMN2MEN1
SCHEMBL29235590 0.80 USP2 (0.38) USP2ALDH1A1ANPEPSMN1; SMN2MEN1
SCHEMBL17517790 0.75
SCHEMBL6986786 0.72 GRIN2D (0.51) MEN1KMT2ACYP2D6
SCHEMBL31441281 0.72 CARM1 (0.44) MEN1KMT2AKDM4ELMNA
SCHEMBL26668860 0.72 CARM1 (0.44) MEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023126006-A1 CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF 厦门赛诺邦格生物科技股份有限公司 2023-07-06 WO disclosed